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This is the third edition of the Lumbar Disc Herniation Clinical Practice Guidelines, succeeding the first and second editions published in June 2005 and July 2011, respectively.
Fourteen members selected from various regions of Japan and representatives of the Japanese Orthopaedic Association secretariat, the International Medical Information Center, and Nankodo Co., Ltd. participated in the kick-off meeting held on July 2, 2018 in the Japanese Orthopaedic Association secretariat meeting room. Decisions made were to search the MEDLINE, ICHUSHI, and Cochrane Reviews databases for new articles in ~10 years from January 2008 and analyze them in the following five areas: epidemiology/ natural course, pathological condition, diagnosis, treatment, and prognosis. At the first meeting, on August 11, 2018, Professor Masahiro Yoshida from Minds was invited and delivered a lecture, and the revision work finally started. In the epidemiology/natural course and pathological condition areas, four and five Back ground question (BQ)s were determined, respectively; these were developed based on the Questions in the second edition. While the diagnosis area was subdivided in the second edition, four BQs related to symptoms, diagnostics, diagnostic imaging, and other imaging/auxiliary diagnosis methodologies were determined. In the treatment area, three BQs, four Clinical question (CQ)s, and one Future research question (FRQ) were determined to cover advances after the second edition was published, such as advent of drugs for neuropathic pain and intradiscal treatment and wider use of endoscopic surgery; in the prognosis area, seven BQs were determined after examination of factors affecting the likelihood of return to work/sport, surgery results, and postoperative course. This edition is a product of many and long discussions among revision committee members to prepare guidelines that facilitate the current Japanese medical system to reflect facts based on scientific evidence supported by the latest knowledge collected from a large number of articles, and that are beneficial for healthcare professionals and patients. We hope that this edition of the guidelines finds effective use in various clinical settings.

